connective tissue

By Targets:	Apoptosis (1) Biochemical Assay Reagents (1) Carbonic Anhydrase (1) Endogenous Metabolite (4) Fluorescent Dye (1) Histamine Receptor (1) Virus Protease (4)
By Research Areas:	Cancer (3) Inflammation/Immunology (5) Neurological Disease (1)

Targets Recommended: MALT1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99288

FG-3019 Pamrevlumab; Anti-Human CTGF Recombinant Antibody	Apoptosis	Cancer
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF) .

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .

HY-N0469

L-Lysine 3 Publications Verification	Endogenous Metabolite Virus Protease	Inflammation/Immunology Cancer
L-lysine is an essential amino acid with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions .

HY-N2682A

(E)-Dehydrodiconiferyl alcohol	Carbonic Anhydrase	Cancer
(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors . And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area .

HY-N0469S

L-Lysine-d3 hydrochloride	Endogenous Metabolite Virus Protease	Inflammation/Immunology
L-Lysine-d₃ (hydrochloride) is the deuterium labeled L-Lysine. L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

HY-N0469S1

L-Lysine-13C6 dihydrochloride	Endogenous Metabolite Virus Protease	Inflammation/Immunology
L-Lysine- ¹³C₆ (dihydrochloride) is the ¹³C-labeled L-Lysine dihydrochloride. L-lysine dihydrochloride is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

HY-N0469S2

L-Lysine-15N-1 dihydrochloride	Endogenous Metabolite Virus Protease	Inflammation/Immunology
L-Lysine- ¹⁵N-1 (dihydrochloride) is the ¹⁵N-labeled L-Lysine. L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

HY-W250143

Toluidine blue (ZnCl2)	Biochemical Assay Reagents	Others
Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.

HY-13508

JNJ-7777120	Histamine Receptor	Inflammation/Immunology
JNJ-7777120 is a potent and selective histamine H₄ receptor antagonist (K_i=4.5 nM). JNJ-7777120 effectively blocks histamine-induced migration of mouse tracheal mast cells from connective tissue to epithelial cells. JNJ-7777120 also significantly blocks neutrophil infiltration in a mouse Zymosan-induced peritonitis model. JNJ-7777120 has a good potential to study antipruritic and anti-inflammatory .

Cat. No.	Product Name	Type

HY-W250143

Toluidine blue (ZnCl2)	Dyes
Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.

Toluidine blue (ZnCl2)

Dyes

Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.

Cat. No.	Product Name	Type

HY-P2738

Collagens	Native Proteins
Collagens are extracellular matrix proteins and show many applications in food, cosmetic, pharmaceutical and biomedical industries. Collagens play an important role in the structure and function of skin, cartilage, bone and connective tissue .

Cat. No.	Product Name	Target	Research Area

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .

HY-P3524

GRGESP	Peptides	Others
GRGESP is a collagen gel contraction inhibitor. GRGESP inhibits the spreading of human fibroblasts inside collagen gels and markedly decreased gel contraction. GRGDSP can be used for the research of connective tissue morphogenesis .

Cat. No.	Product Name	Target	Research Area

HY-P99288

FG-3019 Pamrevlumab; Anti-Human CTGF Recombinant Antibody	Apoptosis	Cancer
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0469

L-Lysine 3 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Endocrine diseases Amino acids Endogenous metabolite Microorganisms Disease markers Nervous System Disorder Inflammation/Immunology Disease Research Fields Cancer	Endogenous Metabolite Virus Protease
L-lysine is an essential amino acid with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions .

HY-N2682A

(E)-Dehydrodiconiferyl alcohol	Monophenols Glycine soya Classification of Application Fields Source classification Lignans Phenols Cyamopsis tetragonoloba (L.) Taub. Phenylpropanoids Plants Compositae Disease Research Fields Cancer	Carbonic Anhydrase
(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors . And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area .

Species:	Human (3) Mouse (1)
Tag:	His (1) Tag Free (1) GST (1) Fc (1)
Source:	HEK293 (2) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P72153

	CCN2/CTGF Protein, Human (His) 1 Publications Verification CCN 2; CCN family member 2; CCN2; connective tissue growth factor; IGFBP-8; IGFBP8; NOV2	Human	E. coli
	CCN2/CTGF Protein, secreted by vascular endothelial cells, crucially promotes chondrocyte proliferation and differentiation, and mediates heparin- and divalent cation-dependent cell adhesion in diverse cell types. Additionally, it enhances fibroblast growth factor-induced DNA synthesis while existing as a monomer and interacting with TSKU. CCN2/CTGF Protein, Human (His) is the recombinant human-derived CCN2/CTGF protein, expressed by E. coli , with N-6*His labeled tag. The total length of CCN2/CTGF Protein, Human (His) is 97 a.a., with molecular weight of ~15.1 kDa.

HY-P70106

	CCN2/CTGF Protein, Human (HEK293) 1 Publications Verification rHuconnective tissue growth factor/CTGF; connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8	Human	HEK293
	CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (HEK293) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with tag free. The total length of CCN2/CTGF Protein, Human (HEK293) is 154 a.a., with molecular weight of ~21.15 kDa.

HY-P70602

	CCN2/CTGF Protein, Human (HEK293, Fc) connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; CTGF; IGFBP8	Human	HEK293
	CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (HEK293, Fc) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CCN2/CTGF Protein, Human (HEK293, Fc) is 323 a.a., with molecular weight of ~115.37 kDa (Non-reducing) and 63.5 & 35 kDa (Reducing), respectively.

HY-P72154

	CCN2/CTGF Protein, Mouse (GST) CCN 2; CCN family member 2; CCN2; connective tissue growth factor; Ctgf; CTGF_HUMAN; Hcs 24; Hcs24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; MGC102839; NOV 2; NOV2	Mouse	E. coli
	CCN2/CTGF protein is a major connective tissue mitochondrial attractant secreted by vascular endothelial cells and promotes chondrocyte proliferation and differentiation. It mediates heparin- and divalent cation-dependent cell adhesion in various cell types, including fibroblasts, myofibroblasts, endothelial cells, and epithelial cells. CCN2/CTGF Protein, Mouse (GST) is the recombinant mouse-derived CCN2/CTGF protein, expressed by E. coli , with N-GST labeled tag. The total length of CCN2/CTGF Protein, Mouse (GST) is 319 a.a., with molecular weight of ~62 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-N0469S1

L-Lysine-13C6 dihydrochloride
L-Lysine- ¹³C₆ (dihydrochloride) is the ¹³C-labeled L-Lysine dihydrochloride. L-lysine dihydrochloride is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

HY-N0469S

L-Lysine-d3 hydrochloride
L-Lysine-d₃ (hydrochloride) is the deuterium labeled L-Lysine. L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

HY-N0469S2

L-Lysine-15N-1 dihydrochloride
L-Lysine- ¹⁵N-1 (dihydrochloride) is the ¹⁵N-labeled L-Lysine. L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

Cat. No.	Product Name	Application	Reactivity

HY-P81103

CTGF Antibody CCN 2; CCN-2; CCN2; connective tissue Growth Factor; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat(predicted: Chicken, Dog, Pig, Cow)
CTGF Antibody is an unconjugated, approximately 36 kDa, rabbit-derived, anti-CTGF polyclonal antibody. CTGF Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, and predicted: chicken, dog, pig, cow background without labeling.

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